Sitagliptin + Metformin, Indication, Dosage, Side Effect

Indication:

Sitagliptin + Metformin is used together to manage type 2 diabetes mellitus in adults when blood sugar isn’t well controlled with metformin alone or other treatments. Metformin lowers blood sugar by decreasing sugar production in the liver and improving how the body uses insulin, while Sitagliptin helps the pancreas release more insulin and reduce sugar made by the liver, especially after meals. This combination targets different parts of the blood sugar process, helping to maintain more stable levels and reduce the risk of diabetes-related complications.

Dosage:

Sitagliptin + Metformin is a combination oral medicine used to treat type 2 diabetes by improving blood sugar control. The dosage depends on the patient’s current treatment and kidney function. A common starting dose is 50 mg Sitagliptin + 500 mg Metformin twice daily, taken with meals to reduce stomach upset. The dose may be gradually increased up to a maximum of 100 mg Sitagliptin + 2000 mg Metformin per day, usually divided into two doses. The goal is to lower blood sugar while minimizing side effects like nausea or diarrhea.

Note:

Always take with food to reduce gastrointestinal side effects.

Not for type 1 diabetes or severe kidney disease.

Regular blood tests are needed to check blood sugar, kidney function, and vitamin B12 levels.

Side Effect:

The most common side effects of SITAGLIPTIN + METFORMIN are:

Nausea, vomiting, stomach upset, diarrhea, headache, weakness. Tell your doctor or pharmacist right away if any of these side effects persist or worsen.

Remember that your doctor has prescribed this medication because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away of any serious side effects, including: signs of kidney problems (such as change in the amount of urine), joint pain, unusual skin blisters, signs of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain).

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times on the days your doctor directs.

This is not a complete list of possible side effects. Contact your doctor or pharmacist if you have any other side effects not listed above.

FAQ:

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SITAGLIPTIN + METFORMIN has different brand names depending on the manufacturer. Some of the brand names are: