Pazopanib, Indication, Dosage, Side Effect
Indication:
Pazopanib is indicated for the treatment of advanced renal cell carcinoma (kidney cancer) and certain types of advanced soft tissue sarcoma in adults who have already received chemotherapy. It works by blocking proteins called tyrosine kinases that help cancer cells grow and form new blood vessels (angiogenesis). By cutting off the tumor’s blood supply, Pazopanib helps slow down or stop the growth and spread of the cancer.
Dosage:
The usual dosage of Pazopanib for adults is 800 mg once daily, taken by mouth on an empty stomach—either 1 hour before or 2 hours after a meal. It is used to treat advanced kidney cancer (renal cell carcinoma) and certain soft tissue sarcomas. The dose may be adjusted by a doctor based on how the patient responds and any side effects experienced, such as high blood pressure, liver enzyme changes, or fatigue. The tablets should be swallowed whole with water and not crushed or broken.
Extra notes:
Liver function tests are done regularly, as Pazopanib can affect liver health.
Taking it with food increases drug levels in the blood, which may lead to more side effects—so timing is important.
Grapefruit and grapefruit juice should be avoided as they can interfere with the drug's metabolism.
Side Effect:
The most common side effects of Pazopanib are:
Dizziness, nausea, vomiting, headache, loss of appetite, weight loss, tiredness, weakness. Tell your doctor or pharmacist right away if any of these side effects persist or worsen.
Remember that your doctor has prescribed this medication because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: symptoms of heart failure (such as swelling ankles/feet, unusual tiredness), signs of an underactive thyroid (such as unusual weight gain, cold intolerance, slow heartbeat), signs of infection (such as fever, chills, persistent sore throat, cough), wounds that do not heal.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times on the days your doctor directs.
This is not a complete list of possible side effects. Contact your doctor or pharmacist if you have any other side effects not listed above.
FAQ:
Frequently Asked Questions Regarding (Pazopanib) / Generic VOTRIENT Pazopanib:
May I inquire about the availability of the generic form of Pazopanib, commonly referred to as/ VOTRIENT, for global distribution?
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What’s the minimum order quantity for the generic version of Pazopanib?
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How much does the generic Pazopanib, sold as or VOTRIENT in various countries, cost?
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Pazopanib has different brand names depending on the manufacturer. Some of the brand names are: