Mexiletine, Indication, Dosage, Side Effect

Indication:

Mexiletine is mainly used to treat serious abnormal heart rhythms, especially ventricular arrhythmias, which are fast, irregular heartbeats that start in the lower chambers of the heart. These types of arrhythmias can be life-threatening if not controlled. Mexiletine works by blocking certain electrical signals in the heart that cause it to beat irregularly, helping to restore a normal and steady rhythm. It is typically used when other antiarrhythmic drugs are not effective or suitable.

Dosage:                               

Mexiletine is an antiarrhythmic medication used to treat serious irregular heartbeats (like ventricular arrhythmias). The usual starting dose for adults is 200 mg taken three times a day (every 8 hours). Depending on how well the patient responds and tolerates the medication, the dose can be adjusted—typically ranging from 200 mg to 300 mg, 2 to 3 times daily. The maximum recommended dose is 1,200 mg per day. In some cases, a lower starting dose is used and gradually increased to avoid side effects like nausea or dizziness.

Note:

Mexiletine should be taken with food to reduce stomach upset.

Regular ECGs and blood tests are needed to monitor heart function and drug levels.

It is usually prescribed when other treatments have not worked or are not suitable.

Patients should not stop taking it suddenly without a doctor’s advice, as this can worsen heart rhythm problems.

Side Effect:

The most common side effects of Mexiletine are:

Nausea, shaking, dizziness, lightheadedness, heartburn, vision problems (such as blurred vision), headache, vomiting, nervousness, or problems with muscle control (coordination difficulties).

Remember that your doctor has prescribed this medication because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: worsening symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), signs of liver problems (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine).

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times on the days your doctor directs.

This is not a complete list of possible side effects. Contact your doctor or pharmacist if you have any other side effects not listed above.

FAQ:

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MEXILETINE has different brand names depending on the manufacturer. Some of the brand names are: