Tofacitinib: Indication, Dosage, Side Effect

Indication

Tofacitinib is used to treat certain autoimmune diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), and moderate to severe ulcerative colitis (UC). These conditions occur when the immune system mistakenly attacks the body’s own tissues. Tofacitinib works by blocking specific enzymes called Janus kinases (JAKs) that are involved in the immune response, helping to reduce inflammation, pain, swelling, and damage in the joints or gut.

Dosage

Tofacitinib is an oral medicine used to treat autoimmune diseases like rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and others. The usual adult dose is 5 mg twice daily or 11 mg once daily (extended-release form), depending on the condition being treated. For ulcerative colitis, the starting dose may be 10 mg twice daily for 8 weeks, followed by a lower maintenance dose. The exact dose can vary based on the patient’s response, kidney or liver function, and risk of side effects.

Extra Notes:

Should be taken with or without food at the same time each day.

Dose may be reduced in patients with kidney or liver problems, or if used with other immune-suppressing drugs.

Regular blood tests are needed to monitor for infections, cholesterol levels, and liver enzymes.

May increase the risk of serious infections, blood clots, or heart problems in some people.

Side Effects-

The most common side effects of Tofacitinib are:

Headache or diarrhea. Tell your doctor or pharmacist right away if any of these side effects persist or worsen.

Remember that your doctor has prescribed this medication because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: unusual tiredness, fast heartbeat, signs of liver disease (such as nausea/vomiting that doesn't stop, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine).

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times on the days your doctor directs.

This is not a complete list of possible side effects. Contact your doctor or pharmacist if you have any other side effects not listed above.

FAQ:

Frequently Asked Questions Regarding (Tofacitinib) / Generic XELJANZ Tofacitinib:

May I inquire about the availability of the generic form of Tofacitinib, commonly referred to as/ XELJANZ, for global distribution?

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What’s the minimum order quantity for the generic version of Tofacitinib?

The smallest amount you can order of (Tofacitinib) depends on what the client or patient needs.

How much does the generic Tofacitinib, sold as or XELJANZ in various countries, cost?

The price of (Tofacitinib) will be shared once we get a valid order from clients or patients.

How is it possible to procure (Tofacitinib), the generic version of XELJANZ?

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Tofacitinib has different brand names depending on the manufacturer. Some of the brand names are: