Elafibranor: Indication, Dosage, Side Effect
Indication:
Elafibranor is primarily being developed and studied for the treatment of Primary Biliary Cholangitis (PBC) and Non-Alcoholic Steatohepatitis (NASH), which are chronic liver diseases. It works by targeting specific receptors in the body (PPAR-α and PPAR-δ) to help reduce liver inflammation, improve liver function, and regulate fat and sugar metabolism. In PBC, it is considered when patients do not respond well to first-line treatment like ursodeoxycholic acid (UDCA).
Dosage:
Elafibranor is typically prescribed at a dose of 80 mg once daily, taken orally. You can take it with or without food, but it's best to take it at the same time each day to help remember. The tablet should be swallowed whole—do not chew, crush, or break it.
Note:
Bile Acid Sequestrants: If you're also taking medications like cholestyramine or colesevelam to lower cholesterol, take Elafibranor at least 4 hours before or after these medications to avoid interaction.
Hepatic Impairment: If you have mild to moderate liver impairment (Child-Pugh A or B), no dose adjustment is needed. However, Elafibranor is not recommended for those with severe liver impairment (Child-Pugh C) or decompensated cirrhosis.
Renal Impairment: No dose adjustment is necessary for patients with renal impairment.
Missed Dose: If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose—do not take two doses at once.
Side Effect:
The most common side effects of Elafibranor are:
Elafibranor, a medicine being studied mainly for liver diseases like non-alcoholic steatohepatitis (NASH), may cause some side effects in certain people. Common side effects can include nausea, diarrhea, abdominal pain, headache, and fatigue. Some individuals might also notice changes in liver enzyme levels, cholesterol levels, or mild digestive discomfort. These side effects are generally manageable but should always be reported to your doctor.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times on the days your doctor directs.
This is not a complete list of possible side effects. Contact your doctor or pharmacist if you have any other side effects not listed above.
FAQ:
Frequently Asked Questions Regarding (Elafibranor) / Generic Catequentinib Elafibranor:
May I inquire about the availability of the generic form of Elafibranor, commonly referred to as/ CATEQUENTINIB, for global distribution?
Certainly! We are able to distribute (Elafibranor) globally, thanks to WTO regulations and our patient support program, which is specifically designed for individual patient treatments.
What’s the minimum order quantity for the generic version of Elafibranor?
The smallest amount you can order of (Elafibranor) depends on what the client or patient needs.
How much does the generic Elafibranor, sold as or Catequentinib in various countries, cost?
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How is it possible to procure (Elafibranor), the generic version of Catequentinib?
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Elafibranor has different brand names depending on the manufacturer. Some of the brand names are: